Efficacy, safety and mechanism of cyclodextrins as absorption enhancers in nasal delivery of peptide and protein drugsMARTTIN, E; VERHOEF, J. C; MERKUS, F. W. H. M et al.Journal of drug targeting. 1998, Vol 6, Num 1, pp 17-36, issn 1061-186XArticle

Influence of food on the bioavailability of spironolactoneOVERDIEK, H. W. P. M; MERKUS, F. W. H. M.Clinical pharmacology and therapeutics. 1986, Vol 40, Num 5, pp 531-536, issn 0009-9236Article

Clinical pharmacokinetics of dapsoneZUIDEMA, J; HILBERS-MODDERMAN, H; MERKUS, F. W. H. M et al.Clinical pharmacokinetics. 1986, Vol 11, Num 4, pp 299-315, issn 0312-5963Article

The influence of drugs on nasal ciliary movementHERMENS, W. A. J. J; MERKUS, F. W. H. M.Pharmaceutical research. 1987, Vol 4, Num 6, pp 445-449, issn 0724-8741Article

Nasal absorption of dihydroergotamine from liquid and powder formulations in rabbitsMARTTIN, E; ROMEIJN, S. G; VERHOEF, J. C et al.Journal of pharmaceutical sciences. 1997, Vol 86, Num 7, pp 802-807, issn 0022-3549Article

The in vitro and in vivo effect of a new non-halogenated corticosteroid ― budesonide ― aerosol on human ciliary epithelial functionDUCHATEAU, G. S. M. J. E; ZUIDEMA, J; MERKUS, F. W. H. M et al.Allergy (Copenhagen). 1986, Vol 41, Num 4, pp 260-265, issn 0105-4538Article

Digitoxin protein binding in hemodialysis patients and patients with normal renal functionLOHMAN, J. J. H. M; HOOYMANS, P. M; MERKUS, F. W. H. M et al.Clinical pharmacy. 1987, Vol 6, Num 7, pp 565-567, issn 0278-2677Article

Bioavailability of propranolol after oral, sublingual, and intranasal administrationDUCHATEAU, G. S. M. J. E; ZUIDEMA, J; MERKUS, F. W. H. M et al.Pharmaceutical research. 1986, Vol 3, Num 2, pp 108-111, issn 0724-8741Article

Simplified solid-phase extraction method for determination of dihydroergotamine in rabbit and human serum using high-performance liquid chromatography with fluorescence detectionROMEIJN, S. G; MARTTIN, E; VERHOEF, J. C et al.Journal of chromatography. B, Biomedical sciences and applications. 1997, Vol 692, Num 1, pp 227-232, issn 1387-2273Article

Effects of absorption enhancers on rat nasal epithelium in vivo : release of marker compounds in the nasal cavityMARTTIN, E; VERHOEF, J. C; ROMEIJN, S. G et al.Pharmaceutical research. 1995, Vol 12, Num 8, pp 1151-1157, issn 0724-8741Article

Bile salts and intranasal drug absorptionDUCHATEAU, G. S. M. J. E; ZUIDEMA, J; MERKUS, F. W. H. M et al.International journal of pharmaceutics. 1986, Vol 31, Num 3, pp 193-199, issn 0378-5173Article

Sustained release properties of an intra-adiposely administered dapsone depot injectionPIETERS, F. A. J. M; ZUIDEMA, J; MERKUS, F. W. H. M et al.International journal of leprosy. 1986, Vol 54, Num 3, pp 383-388, issn 0020-7349Article

Hypocalcemic effect of salmon calcitonin following single and repeated nasal and intravenous administration in young rabbitsSCHIPPER, N. G. M; ROMEIJN, S. G; VERHOEF, J et al.Calcified tissue international. 1994, Vol 54, Num 1, pp 50-55, issn 0171-967XArticle

Influence of levocabastine suspension on ciliary beat frequency and mucociliary clearanceMERKUS, F. W. H. M; SCHÜSLER-VAN HEES, M. T. I. W.Allergy, European journal of allergy and clinical immunology. 1992, Vol 47, Num 3, pp 230-233Article

The nasal mucociliary clearance : relevance to nasal drug deliverySHIPPER, N. G. M; COOS VERHOEF, J; MERKUS, F. W. H. M et al.Pharmaceutical research. 1991, Vol 8, Num 7, pp 807-814, issn 0724-8741, 8 p.Article

Liquid chromatographic determination of β-cyclodextrin derivatives based on fluorescence enhancement after inclusion complexationREEUWIJK, H. J. E. M; IRTH, H; TJADEN, U. R et al.Journal of chromatography. Biomedical applications. 1993, Vol 614, Num 1, pp 95-101, issn 0378-4347Article

Absorption enhancers in nasal insulin delivery and their influence on nasal ciliary functioningSCHIPPER, N. G. M; VERHOEF, J; ROMEIJN, S. G et al.Journal of controlled release. 1992, Vol 21, Num 1-3, pp 173-185, issn 0168-3659Conference Paper

Absorption enhancing effect of cyclodextrins on intranasally administered insulin in ratsMERKUS, F. W. H. M; COOS VERHOEF, J; ROMEIJN, S. G et al.Pharmaceutical research. 1991, Vol 8, Num 5, pp 588-592, issn 0724-8741, 5 p.Article

Nasal absorption enhancement of 17β-estradiol by dimethyl-β-cyclodextrin in rabbits and ratsHERMENS, W. A. J. J; DEURLOO, M. J. M; ROMEYN, S. G et al.Pharmaceutical research. 1990, Vol 7, Num 5, pp 500-503, issn 0724-8741, 4 p.Article

Transport of peptide and protein drugs across biological membranesVERHOEF, J. C; BODDE, H. E; DE BOER, A. G et al.European journal of drug metabolism and pharmacokinetics. 1990, Vol 15, Num 2, pp 83-93, issn 0378-7966, 11 p.Conference Paper

Normalization of plasma vitamin B₁₂ concentration by intranasal hydroxocobalamin in vitamin B₁₂-deficient PatientsSLOT, W. B; MERKUS, F. W. H. M; VAN DEVENTER, S. J. H et al.Gastroenterology (New York, NY. 1943). 1997, Vol 113, Num 2, pp 430-433, issn 0016-5085Article

Nasal absorption of 17-beta-estradiol and progesterone from a dimethyl-cyclodextrin inclusion formulation in ratsSCHIPPER, N. G. M; HERMENS, W. A. J. J; ROMEYN, S. G et al.International journal of pharmaceutics. 1990, Vol 64, Num 1, pp 61-66, issn 0378-5173, 6 p.Article

The parmacokinetics of artemisinin after oral, intramuscular and rectal administration to volunteersTITULAER, H. A. C; ZUIDEMA, J; KAGER, P. A et al.Journal of pharmacy and pharmacology. 1990, Vol 42, Num 11, pp 810-813, issn 0022-3573, 4 p.Article

Absorption enhancement of intranasally administered insulin by sodium taurodihydrofusidate (STDHF) in rabbits and ratsDEURLOO, M. J. M; HERMENS, W. A. J. J; ROMEYN, S. G et al.Pharmaceutical research. 1989, Vol 6, Num 10, pp 853-856, issn 0724-8741Article

Factors affecting the determination of unbound carbamazepine concentrations in plasmaLOHMAN, J. J. H. M; MERKUS, F. W. H. M; COSTONGS, G. M. P. J et al.Pharmaceutical research. 1984, Num 1, issn 0724-8741, 49Article